Cross bridging theory for muscle contraction

    The cross-bridge theory of muscle contraction states how force is produced, and how the filaments actin and myosin are moved relative to each other to produce muscle shortening. In the cross-bridge theory, sidepieces that are fixed in a regular pattern on the myosin filament (cross-bridges) are thought to undergo cyclic attachment and detachment to specific binding sites on the actin filament. During an attachment/detachment cycle, the cross-bridge head is thought to undergo a rotation and so pull the actin filament relative to the myosin. one cross-bridge cycle is thought to occur with the energy gained from the hydrolysis of one adenosine triphosphate (ATP).

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